Integrin beta 4 antibody (AA 1772-1822)

Catalog No. ABIN7450375

This Rabbit Polyclonal antibody specifically detects Integrin beta 4 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for Integrin beta 4 antibody (AA 1772-1822) (ABIN7450375)

Target: Integrin beta 4 (ITGB4)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Integrin beta 4 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-Integrin beta 4 Antibody

Binding Specificity: AA 1772-1822

Purpose: Rabbit anti-ITGB4/CD104/Integrin beta-4 Antibody, Affinity Purified

Predicted Reactivity: Mouse,Rat

Purification: Affinity Purified

Immunogen: Between AA 1772 and 1822

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Integrin beta 4

Target: Integrin beta 4 (ITGB4)

Alternative Name: ITGB4/CD104/Integrin beta-4

Background: Background: The gene ITGB4, also known as CD104, encodes for the integrin beta subunit integrin beta-4. Integrin alpha-6/beta-4 is a receptor for laminin and plays a critical structural role in the hemidesmosome of epithelial cells. ITGA6:ITGB4 is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in ITGB4/CD104 are associated with epidermolysis bullosa with pyloric atresia [taken from NCBI Entrez Gene (Gene ID: 3691) and UniProtKB (Entry: P16144)].

Gene ID: 3691

UniProt: P16144

Pathways: Integrin Complex