SORD antibody (AA 307-357)

Catalog No. ABIN7450756

This Rabbit Polyclonal antibody specifically detects SORD in WB and IP. It exhibits reactivity toward Human.

Quick Overview for SORD antibody (AA 307-357) (ABIN7450756)

Target: SORD (Sorbitol Dehydrogenase (SORD))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SORD antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-SORD Antibody

Binding Specificity: AA 307-357

Purpose: Rabbit anti-SORD Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 307 and 357

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SORD

Target: SORD (Sorbitol Dehydrogenase (SORD))

Alternative Name: SORD

Background: Background: Sorbitol dehydrogenase (SORD) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase, makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor [taken from NCBI Entrez Gene (Gene ID: 6652)].

Gene ID: 6652

NCBI Accession: NP_003095

UniProt: Q00796