H13 antibody (AA 327-377)
Quick Overview for H13 antibody (AA 327-377) (ABIN7450765)
Target
See all H13 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 327-377
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Purpose
- Rabbit anti-SPP Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogen
- Between AA 327 and 377
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Isotype
- IgG
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Application Notes
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- H13 (Histocompatibility 13 (H13))
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Alternative Name
- SPP
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Background
- Background: Signal peptide peptidase (SPP) catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein, resulting in the release of the fragment from the ER membrane into the cytoplasm. SPP is required to generate lymphocyte cell surface (HLA-E) epitopes derived from MHC class I signal peptides. It may play a role in graft rejection (By similarity) [taken from the Universal Protein Resource (UniProt) Q8TCT9].
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Gene ID
- 81502
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NCBI Accession
- NP_110416
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UniProt
- Q8TCT9
Target
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