STRAP antibody (AA 300-350)

Catalog No. ABIN7450785

This anti-STRAP antibody is a Rabbit Polyclonal antibody detecting STRAP in WB and IP. Suitable for Human and Mouse.

Quick Overview for STRAP antibody (AA 300-350) (ABIN7450785)

Target: STRAP (Serine/threonine Kinase Receptor Associated Protein (STRAP))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STRAP antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-STRAP Antibody

Binding Specificity: AA 300-350

Purpose: Rabbit anti-STRAP Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 300 and 350

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for STRAP

Target: STRAP (Serine/threonine Kinase Receptor Associated Protein (STRAP))

Alternative Name: STRAP

Background: Background: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Serine-threonine kinase receptor-associated protein (STRAP) plays a role in the cellular distribution of the SMN complex. It negatively regulates TGF-beta signaling but positively regulates the PDPK1 kinase activity by enhancing its autophosphorylation and by significantly reducing the association of PDPK1 with 14-3-3 protein [taken from the Universal Protein Resource (UniProt) Q9Y3F4].

Gene ID: 11171

NCBI Accession: NP_009109

UniProt: Q9Y3F4