VTA1 antibody (AA 150-200)

Catalog No. ABIN7450902

This anti-VTA1 antibody is a Rabbit Polyclonal antibody detecting VTA1 in WB and IP. Suitable for Human.

Quick Overview for VTA1 antibody (AA 150-200) (ABIN7450902)

Target: VTA1 (Vps20-Associated 1 Homolog (VTA1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VTA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-VTA1 Antibody

Binding Specificity: AA 150-200

Purpose: Rabbit anti-VTA1/LIP5 Antibody, Affinity Purified

Predicted Reactivity: Mouse,Bovine,Orangutan

Purification: Affinity Purified

Immunogen: Between AA 150 and 200

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for VTA1

Target: VTA1 (Vps20-Associated 1 Homolog (VTA1))

Alternative Name: VTA1/LIP5

Background: Background: VTA1 is involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. VTA1 is thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. It is involved in the sorting and down-regulation of EGFR (By similarity) [taken from the Universal Protein Resource (UniProt) Q9NP79].

Gene ID: 51534

UniProt: Q9NP79