HSD17B4 antibody (AA 600-650)

Catalog No. ABIN7451084

The Rabbit Polyclonal anti-HSD17B4 antibody has been validated for IP. It is suitable to detect HSD17B4 in samples from Human.

Quick Overview for HSD17B4 antibody (AA 600-650) (ABIN7451084)

Target: HSD17B4 (Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSD17B4 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-HSD17B4 Antibody

Binding Specificity: AA 600-650

Purpose: Rabbit anti-HSD17B4/MFE-2/17-beta-HSD4 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 600 and 650

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. ABIN7451084 has not performed satisfactorily when used for WB of HSD17B4/MFE-2/17-beta-HSD4 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of HSD17B4/MFE-2/17.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for HSD17B4

Target: HSD17B4 (Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4))

Alternative Name: HSD17B4/MFE-2/17-beta-HSD4

Background: Background: HSD17B4 is a bifunctional enzyme acting on the peroxisomal beta-oxidation pathway for fatty acids.It catalyzes the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids [taken from the Universal Protein Resource (UniProt) P51659].

Gene ID: 3295

NCBI Accession: NP_000405

UniProt: P51659

Pathways: Monocarboxylic Acid Catabolic Process