UCHL5 antibody (AA 279-329)

Catalog No. ABIN7451377

This Rabbit Polyclonal antibody specifically detects UCHL5 in IP. It exhibits reactivity toward Human.

Quick Overview for UCHL5 antibody (AA 279-329) (ABIN7451377)

Target: UCHL5 (Ubiquitin Carboxyl-terminal Hydrolase L5 (UCHL5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UCHL5 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-UCHL5 Antibody

Binding Specificity: AA 279-329

Purpose: Rabbit anti-UCH37 Antibody, Affinity Purified

Predicted Reactivity: Mouse,Bovine,Pig

Purification: Affinity Purified

Immunogen: Between AA 279 and 329

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. Use rabbit anti-UCH37 antibody ABIN7450873.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for UCHL5

Target: UCHL5 (Ubiquitin Carboxyl-terminal Hydrolase L5 (UCHL5))

Alternative Name: UCH37

Background: Background: Ubiquitin C-terminal hydrolase UCH37 is a protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. UCH37 is a deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. It is a putative regulatory component of the INO80 complex, however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1 [taken from the Universal Protein Resource (UniProt) Q9Y5K5].

Gene ID: 51377

NCBI Accession: NP_057068

UniProt: Q9Y5K5