DTNBP1 antibody (AA 251-301)

Catalog No. ABIN7451436

This anti-DTNBP1 antibody is a Rabbit Polyclonal antibody detecting DTNBP1 in IP. Suitable for Human.

Quick Overview for DTNBP1 antibody (AA 251-301) (ABIN7451436)

Target: DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DTNBP1 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-DTNBP1 Antibody

Binding Specificity: AA 251-301

Purpose: Rabbit anti-Dysbindin1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 251 and 301

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for DTNBP1

Target: DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))

Alternative Name: Dysbindin1

Background: Background: Dysbindin1 may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations in the DTNBP1 gene are associated with Hermansky-Pudlak syndrome type 7. This gene may also be associated with schizophrenia [taken from NCBI Entrez Gene (Gene ID: 84062)].

Gene ID: 84062

NCBI Accession: NP_115498

UniProt: Q96EV8

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling