ITGA6 antibody (AA 50-100)

Catalog No. ABIN7451462

The Rabbit Polyclonal anti-ITGA6 antibody has been validated for IP. It is suitable to detect ITGA6 in samples from Human.

Quick Overview for ITGA6 antibody (AA 50-100) (ABIN7451462)

Target: ITGA6 (Integrin, alpha 6 (ITGA6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGA6 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-ITGA6 Antibody

Binding Specificity: AA 50-100

Purpose: Rabbit anti-Integrin Alpha 6 Antibody, Affinity Purified

Predicted Reactivity: Mouse

Purification: Affinity Purified

Immunogen: Between AA 50 and 100

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for ITGA6

Target: ITGA6 (Integrin, alpha 6 (ITGA6))

Alternative Name: Integrin Alpha 6

Background: Background: Integrin alpha 6 forms heterodimers with integrin beta 1 or beta 4 and functions as a receptor for the extracellular matrix protein, laminin. Integrin alpha 6 is encoded by the ITGA6 gene. Defects in ITGA6 are a cause of epidermolysis bullosa letalis with pyloric atresia (EB-PA) [MIM:226730], also known as junctional epidermolysis bullosa with pyloric atresia (PA-JEB) or aplasia cutis congenita with gastrointestinal atresia. EB-PA is an autosomal recessive, frequently lethal, epidermolysis bullosa with variable involvement of skin, nails, mucosa, and with variable effects on the digestive system [taken from the Universal Protein Resource (UniProt) P23229].

Gene ID: 3655

UniProt: P23229

Pathways: CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex