KLHL12 antibody (AA 150-200)

Catalog No. ABIN7451467

This Rabbit Polyclonal antibody specifically detects KLHL12 in IP. It exhibits reactivity toward Human.

Quick Overview for KLHL12 antibody (AA 150-200) (ABIN7451467)

Target: KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLHL12 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-KLHL12 Antibody

Binding Specificity: AA 150-200

Purpose: Rabbit anti-KLHL12 Antibody, Affinity Purified

Predicted Reactivity: Mouse,Rat,Bovine

Purification: Affinity Purified

Immunogen: between AA 150 and 200

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for KLHL12

Target: KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))

Alternative Name: KLHL12

Background: Background: Kelch-like protein 12 (KLHL12) serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. KLHL12 negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3 [taken from the Universal Protein Resource (UniProt) Q53G59].

Gene ID: 59349

NCBI Accession: NP_067646

UniProt: Q53G59