Erythrocyte Ankyrin antibody (AA 1831-1881)

Catalog No. ABIN7451632

This Rabbit Polyclonal antibody specifically detects Erythrocyte Ankyrin in WB and IP. It exhibits reactivity toward Human.

Quick Overview for Erythrocyte Ankyrin antibody (AA 1831-1881) (ABIN7451632)

Target: Erythrocyte Ankyrin (ANK1) (Ankyrin 1, Erythrocytic (ANK1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Erythrocyte Ankyrin antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-Erythrocyte Ankyrin Antibody

Binding Specificity: AA 1831-1881

Purpose: Rabbit anti-Ankyrin 1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1831 and 1881

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Erythrocyte Ankyrin

Target: Erythrocyte Ankyrin (ANK1) (Ankyrin 1, Erythrocytic (ANK1))

Alternative Name: Ankyrin 1

Background: Background: Ankyrin 1 is a member of the ankyrin family of proteins that function to link integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact, and the maintenance of specialized membrane domains. Ankyrin 1 was first discovered in erythrocytes, but since has also been found in brain and muscles. Mutations in erythrocytic ankyrin 1 have been associated in approximately half of all patients with hereditary spherocytosis [taken from NCBI Entrez Gene (Gene ID: 286].

Gene ID: 286

NCBI Accession: NP_065209

UniProt: P16157

Pathways: Synaptic Membrane