DHX16 antibody (AA 991-1041)

Catalog No. ABIN7451736

This anti-DHX16 antibody is a Rabbit Polyclonal antibody detecting DHX16 in WB and IP. Suitable for Human.

Quick Overview for DHX16 antibody (AA 991-1041) (ABIN7451736)

Target: DHX16 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 16 (DHX16))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DHX16 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-DHX16 Antibody

Binding Specificity: AA 991-1041

Purpose: Rabbit anti-DHX16 Antibody, Affinity Purified

Predicted Reactivity: Chimpanzee

Purification: Affinity Purified

Immunogen: between AA 991 and 1041

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for DHX16

Target: DHX16 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 16 (DHX16))

Alternative Name: DHX16

Background: Background: DHX16 is a member of the DEAH-box family of proteins that possesses several conserved motifs which include the highly conserved DEAH (Asp-Glu-Ala-His) amino acid sequence motif. The major activity of DEAH-box proteins is to function as ATP-dependent RNA helicases. RNA helicases play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. DH16 was originally identified as DBP2 and discovered to be a functional homolog of the yeast RNA helicase and ATPase, Cdc28/Prp68. DHX16 appears to play a key role in nonsense-mediated mRNA decay (NMD) as well as rRNA processing.

Gene ID: 8449

NCBI Accession: NP_003578

UniProt: O60231