NFX1 antibody (AA 1-50)

Catalog No. ABIN7451894

The Rabbit Polyclonal anti-NFX1 antibody has been validated for WB and IP. It is suitable to detect NFX1 in samples from Human.

Quick Overview for NFX1 antibody (AA 1-50) (ABIN7451894)

Target: NFX1 (Nuclear Transcription Factor, X-Box Binding 1 (NFX1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-NFX1 Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit anti-NFX1 Antibody, Affinity Purified

Predicted Reactivity: Mouse

Purification: Affinity Purified

Immunogen: between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for NFX1

Target: NFX1 (Nuclear Transcription Factor, X-Box Binding 1 (NFX1))

Alternative Name: NFX1

Background: Background: NFX1 (nuclear transcription factor, X box-binding protein 1) binds to the X-box motif of MHC class II genes and represses their expression. NFX1 may play an important role in regulating the duration of an inflammatory response by limiting the period in which MHC class II molecules are induced by interferon-gamma. Isoform 3 of NFX1 binds to the X-box motif of TERT promoter and represses its expression. Together with PABPC1 or PABPC4, isoform 1 acts as a coactivator for TERT expression [taken from the Universal Protein Resource (UniProt) Q12986].

Gene ID: 4799

NCBI Accession: NP_002495

UniProt: Q12986