RAPGEF6 antibody (AA 625-675)

Catalog No. ABIN7451948

The Rabbit Polyclonal anti-RAPGEF6 antibody has been validated for WB and IP. It is suitable to detect RAPGEF6 in samples from Human.

Quick Overview for RAPGEF6 antibody (AA 625-675) (ABIN7451948)

Target: RAPGEF6 (Rap Guanine Nucleotide Exchange Factor (GEF) 6 (RAPGEF6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAPGEF6 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-RAPGEF6 Antibody

Binding Specificity: AA 625-675

Purpose: Rabbit anti-PDZ-GEF2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 625 and 675

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for RAPGEF6

Target: RAPGEF6 (Rap Guanine Nucleotide Exchange Factor (GEF) 6 (RAPGEF6))

Alternative Name: PDZ-GEF2

Background: Background: PDZ-GEF2 is a guanine nucleotide exchange factor (GEF) for Rap GTPases. It contains one PDZ-signaling domain, a Ras-association (RA) domain, and a region related to a cyclic nucleotide binding domain (RCBD). PDZ-GEF1 functions to catalyze the exchange of GDP for GTP and activate Rap1A, Rap1B, and Rap2B GTPase activity. PDZ-GEF2 has been shown to activate Rap1A and Rap1B to promote the maturation of cell-cell adherens junctions.

Gene ID: 51735

NCBI Accession: NP_057424

UniProt: Q8TEU7