RAD18 antibody (AA 445-495)

Catalog No. ABIN7451995

This Rabbit Polyclonal antibody specifically detects RAD18 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for RAD18 antibody (AA 445-495) (ABIN7451995)

Target: RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAD18 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-RAD18 Antibody

Binding Specificity: AA 445-495

Purpose: Rabbit anti-Rad18 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 445 and 495

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for RAD18

Target: RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))

Alternative Name: Rad18

Background: Background: Rad18 is an E3 ubiquitin-protein ligase that associates with the E2 ubiquitin conjugating enzyme UBE2B (Rad6b) and monoubiquitinates PCNA on stalled replication forks. This activity promotes the recruitment of DNA repair polymerases such as DNA polymerase eta (Poleta) and translesion synthesis at DNA lesions.

Gene ID: 56852

NCBI Accession: NP_064550

UniProt: Q9NS91