WNK3 antibody (AA 1-50)
Quick Overview for WNK3 antibody (AA 1-50) (ABIN7452168)
Target
See all WNK3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
 - AA 1-50
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Purpose
 - Rabbit anti-WNK3 Antibody, Affinity Purified
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Purification
 - Affinity Purified
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Immunogen
 - between AA 1 and 50
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Isotype
 - IgG
 
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Application Notes
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Restrictions
 - For Research Use only
 
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Concentration
 - 200 μg/mL
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Buffer
 - Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Preservative
 - Sodium azide
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Precaution of Use
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
 - 4 °C
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Expiry Date
 - 12 months
 
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- WNK3 (WNK Lysine Deficient Protein Kinase 3 (WNK3))
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Alternative Name
 - WNK3
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Background
 - Background: WNK3 (With No Lysine 3) is a member of the WNK family of serine-threonine kinases which includes WNK1, WNK2, WNK3, and WNK4. The WNK family of kinases has been observed to play a role in several cellular processes which include ion balance, signal transduction, survival, proliferation and organ development. WNK3 appears to play a role in NaCl, water, and blood pressure homeostasis but has properties distinct from the other WNK family members. WNK3 is expressed throughout the nephron, particularly at intercellular junctions, and its kinase activity has been shown to regulate the activity of ion transporters such as the Na-K-2Cl and Na-Cl co-transporters.
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Gene ID
 - 65267
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NCBI Accession
 - NP_001002838
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UniProt
 - Q9BYP7
 
Target
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