HEXIM2 antibody (AA 1-50)

Catalog No. ABIN7452248

The Rabbit Polyclonal anti-HEXIM2 antibody has been validated for IP. It is suitable to detect HEXIM2 in samples from Human.

Quick Overview for HEXIM2 antibody (AA 1-50) (ABIN7452248)

Target: HEXIM2 (Hexamthylene Bis-Acetamide Inducible 2 (HEXIM2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HEXIM2 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-HEXIM2 Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit anti-HEXIM2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. ABIN7452248 has not performed satisfactorily when used for WB of HEXIM2 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of HEXIM2.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for HEXIM2

Target: HEXIM2 (Hexamthylene Bis-Acetamide Inducible 2 (HEXIM2))

Alternative Name: HEXIM2

Background: Background: HEXIM2 (Hexamethylene bis-acetamide-inducible protein 2) is a transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA, HEXIM2 sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. [taken from the Universal Protein Resource (UniProt) Q96MH2].

Gene ID: 124790

NCBI Accession: NP_653209

UniProt: Q96MH2