EYA3 antibody (AA 30-60)

Catalog No. ABIN7452325

This Rabbit Polyclonal antibody specifically detects EYA3 in IP. It exhibits reactivity toward Human.

Quick Overview for EYA3 antibody (AA 30-60) (ABIN7452325)

Target: EYA3 (Eyes Absent Homolog 3 (EYA3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EYA3 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-EYA3 Antibody

Binding Specificity: AA 30-60

Purpose: Rabbit anti-EYA3 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 30 and 60

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-EYA3 antibody ABIN7453703.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for EYA3

Target: EYA3 (Eyes Absent Homolog 3 (EYA3))

Alternative Name: EYA3

Background: Background: EYA3 (eyes absent homolog 3) functions as a tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). EYA3 promotes efficient DNA repair by dephosphorylating H2AX and promoting the recruitment of DNA repair complexes containing MDC1. EYA3 coactivates SIX1. Together with SIX1 and DACH2 EYA3 seems to be involved in myogenesis. EYA3 may be involved in development of the eye [taken from the Universal Protein Resource (UniProt) Q99504].

Gene ID: 2140

NCBI Accession: NP_001981

UniProt: Q99504

Pathways: Positive Regulation of Response to DNA Damage Stimulus