OBFC2A antibody (AA 150-200)

Catalog No. ABIN7452719

The Rabbit Polyclonal anti-OBFC2A antibody is suitable to detect OBFC2A in samples from Human. It has been validated for IP.

Quick Overview for OBFC2A antibody (AA 150-200) (ABIN7452719)

Target: OBFC2A (Oligonucleotide/oligosaccharide-Binding Fold Containing 2A (OBFC2A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OBFC2A antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-OBFC2A Antibody

Binding Specificity: AA 150-200

Purpose: Rabbit anti-OBFC2A Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 150 and 200

Isotype: IgG

Application Details

Application Notes:

IP: 5 - 10 μg/mg lysate

WB: Not recommended. ABIN7452719 has not performed satisfactorily when used for WB of OBFC2A in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of OBFC2A.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for OBFC2A

Target: OBFC2A (Oligonucleotide/oligosaccharide-Binding Fold Containing 2A (OBFC2A))

Alternative Name: OBFC2A

Background: Background: OBFC2A is also known as hSSB2 or SSB2 and is a homolog of hSSB1 (OBFC2B). OBFC2A, as well as OBFC2B are single-stranded binding proteins that contain an oligonucleotide/oliosaccharide binding fold (OB-fold). OB-fold proteins associate with each other to form multi-OB-fold complexes that associate with DNA-processing complexes that participate in DNA damage repair and replication. OBFC2A has been shown to protect genomic stability, and it is hypothesized that its participation in the DNA damage response may involve RAD51 and the ATM signaling pathway.

Gene ID: 64859

NCBI Accession: NP_001026886

UniProt: Q96AH0