AFF4 antibody (AA 1113-1163)

Catalog No. ABIN7452792

This anti-AFF4 antibody is a Rabbit Polyclonal antibody detecting AFF4 in IP. Suitable for Human.

Quick Overview for AFF4 antibody (AA 1113-1163) (ABIN7452792)

Target: AFF4 (AF4/FMR2 Family, Member 4 (AFF4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AFF4 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-AFF4 Antibody

Binding Specificity: AA 1113-1163

Purpose: Rabbit anti-MCEF Antibody, Affinity Purified

Predicted Reactivity: Mouse

Purification: Affinity Purified

Immunogen: between AA 1113 and 1163

Isotype: IgG

Application Details

Application Notes:

IP: 5 - 15 μg/mg lysate

WB: Not recommended

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for AFF4

Target: AFF4 (AF4/FMR2 Family, Member 4 (AFF4))

Alternative Name: MCEF

Background: Background: Major CDK9 elongation factor-associated protein (MCEF) is also known as AFF4 AF4/FMR2 family member 4. This family of proteins includes the AF4 proto-oncogene and FMR2 (fragile X E mental retardation syndrome) nuclear proteins. MCEF is a component of the cyclin-dependent kinase pair (CDK9/cyclin T1) complex. A chromosomal aberration involving AFF4 is found in acute lymphoblastic leukemia (ALL).

Gene ID: 27125

NCBI Accession: NP_055238

UniProt: Q9UHB7