BCKDHA antibody (pSer292)

Catalog No. ABIN7452999

This anti-BCKDHA antibody is a Rabbit Polyclonal antibody detecting BCKDHA in WB. Suitable for Human and Mouse.

Quick Overview for BCKDHA antibody (pSer292) (ABIN7452999)

Target: BCKDHA (Branched Chain Keto Acid Dehydrogenase E1, alpha Polypeptide (BCKDHA))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCKDHA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BCKDHA Antibody

Binding Specificity: pSer292

Purpose: Rabbit anti-BCKDHA, Phospho (S292) Antibody, Affinity Purified

Predicted Reactivity: Rat,Bovine,Chimpanzee

Purification: Affinity Purified

Immunogen: surrounding serine 292

Isotype: IgG

Application Details

Application Notes:

IP: Not recommended

WB: 1:10,000 - 1:25,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Phosphate Buffered Saline (PBS) containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for BCKDHA

Target: BCKDHA (Branched Chain Keto Acid Dehydrogenase E1, alpha Polypeptide (BCKDHA))

Alternative Name: BCKDHA

Background: Background: BCKDHA (branched chain keto acid dehydrogenase E1, alpha polypeptide) is a component of the branched-chain alpha-keto acid (BCAA) dehydrogenase (BCKD) complex. The BCKD complex is an inner mitochondrial enzyme complex that catalyzes the second major step in the catabolism of the branched-chain amino acids leucine, isoleucine, and valine. The BCKD complex consists of three catalytic components: a heterotetrameric (alpha2-beta2) branched-chain alpha-keto acid decarboxylase (E1), a dihydrolipoyl transacylase (E2), and a dihydrolipoamide dehydrogenase (E3). Mutations in this gene result in maple syrup urine disease, type IA [taken from NCBI Entrez Gene (Gene ID: 593)].

Gene ID: 593

NCBI Accession: NP_000700

UniProt: P12694