VSX2 antibody (AA 251-361)

Catalog No. ABIN718976

The Rabbit Polyclonal anti-VSX2 antibody has been validated for WB and ELISA. It is suitable to detect VSX2 in samples from Human.

Quick Overview for VSX2 antibody (AA 251-361) (ABIN718976)

Target: VSX2 (Visual System Homeobox 2 (VSX2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VSX2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-VSX2 Antibody

Binding Specificity: AA 251-361

Cross-Reactivity: Human, Mouse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CHX10

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for VSX2

Target: VSX2 (Visual System Homeobox 2 (VSX2))

Alternative Name: CHX10

Background:

Synonyms: C elegans ceh 10 homeo domain containing homolog, Ceh 10 homeo domain containing homolog C. elegans, Ceh 10 homeo domain containing homolog, Ceh 10 homeodomain containing homolog, Ceh 10 homeodomain containing homolog C. elegans, Ceh10 homeo domain containing homolog, Ceh10 homeodomain containing homolog, CHX 10, Homeobox protein CHX 10, Homeobox protein CHX10, HOX 10, HOX10, MCOP 2, MCOP2, MCOPCB 3, MCOPCB3, RET 1, RET1, Vsx 2, Vsx2.

Background: CHX10 is a 40 kDa homeodomain protein of the paired-like class that is essential for development of the mammalian eye. Mutations in CHX10 cause microphthalmia, a cause of congenital blindness in humans, and the ocular retardation (or) phenotype in mice. In the developing mouse retina CHX10 is expressed in retinal progenitors, while in the mature retina, CHX10 expression becomes restricted to bipolar neurons. Concurrent with these expression patterns, the CHX10-/- (or) retina is thin due to a defect in proliferation of retinal progenitors, and lacks bipolar neurons. CHX10 is also expressed in the developing brainstem, thalamus, and spinal cord.

Gene ID: 338917

Pathways: Dopaminergic Neurogenesis