PARD3 antibody (AA 1306-1356)

Catalog No. ABIN7453156

This Rabbit Polyclonal antibody specifically detects PARD3 in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for PARD3 antibody (AA 1306-1356) (ABIN7453156)

Target: PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PARD3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PARD3 Antibody

Binding Specificity: AA 1306-1356

Purpose: Rabbit anti-PARD3 Antibody, Affinity Purified

Predicted Reactivity: Rat

Purification: Affinity Purified

Immunogen: Between AA 1306 and 1356

Isotype: IgG

Application Details

Application Notes:

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PARD3

Target: PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))

Alternative Name: PARD3

Background: Background: Partitioning defective 3 homolog (Par3) is an adapter protein involved in asymmetrical cell division and cell polarization processes. It seems to play a central role in the formation of epithelial tight junctions and targets the phosphatase PTEN to cell junctions (By similarity). Par3 association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Par3 is required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons [taken from the Universal Protein Resource (UniProt) Q8TEW0].

Gene ID: 56288

NCBI Accession: NP_062565

UniProt: Q8TEW0

Pathways: Cell-Cell Junction Organization