RanBP3 antibody (AA 150-200)

Catalog No. ABIN7453398

Product Details anti-RanBP3 Antibody

Target: RanBP3 (RANBP3) (RAN Binding Protein 3 (RANBP3))

Binding Specificity: AA 150-200

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RanBP3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunoprecipitation (IP)

Purpose: Rabbit anti-RanBP3 Antibody, Affinity Purified

Predicted Reactivity: Orangutan

Purification: Affinity Purified

Immunogen: between AA 150 and 200

Isotype: IgG

Application Details

Application Notes:

IHC-IF: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for RanBP3

Target: RanBP3 (RANBP3) (RAN Binding Protein 3 (RANBP3))

Alternative Name: RanBP3 (RANBP3 Products)

Background: Background: Ran binding protein 3 (RanBP3) is a Ran (ras-related nuclear protein) binding protein and a component of a nuclear transport complex that functions to export proteins out of the nucleus. RanBP3 binds the nucleocytoplasmic transport receptor, CRM1, and facilitates the export of CRM1 substrates. Recently it has been shown that RanBP3 function is regulated by the Ras/ERK/RSK and PI3K/Akt signaling pathway. This finding has provided a link between nuclear transport, cell signaling, and cell fate.

Gene ID: 8498

NCBI Accession: NP_015561

UniProt: Q9H6Z4