TET2 antibody (AA 100-150)

Catalog No. ABIN7453557

This anti-TET2 antibody is a Rabbit Polyclonal antibody detecting TET2 in WB, IP and IHC (fp). Suitable for Human.

Quick Overview for TET2 antibody (AA 100-150) (ABIN7453557)

Target: TET2 (Tet Methylcytosine Dioxygenase 2 (TET2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TET2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-TET2 Antibody

Binding Specificity: AA 100-150

Purpose: Rabbit anti-TET2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 100 and 150

Isotype: IgG

Application Details

Application Notes:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for TET2

Target: TET2 (Tet Methylcytosine Dioxygenase 2 (TET2))

Alternative Name: TET2

Background: Background: TET2 (tet methylcytosine dioxygenase 2) catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. TET2 is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders [taken from NCBI Entrez Gene (Gene ID: 54790)].

Gene ID: 54790

NCBI Accession: NP_001120680

UniProt: Q6N021

Pathways: Warburg Effect