Cullin 4A antibody (C-Term)

Catalog No. ABIN7453591

This Rabbit Polyclonal antibody specifically detects Cullin 4A in WB, IP and IHC (fp). It exhibits reactivity toward Human and Mouse.

Quick Overview for Cullin 4A antibody (C-Term) (ABIN7453591)

Target: Cullin 4A (CUL4A)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cullin 4A antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-Cullin 4A Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-Cul4a Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 700 and C-term

Isotype: IgG

Application Details

Application Notes:

IHC: 1:1,000 to 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:10,000 - 1:25,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Cullin 4A

Target: Cullin 4A (CUL4A)

Alternative Name: Cul4a

Background: Background: Cul4a is a member of the cullin group of proteins and functions as a scaffold to bring together ubiquitin E3 ligases, E2 conjugating enzyme, and substrate proteins to mediate the ubiquitination of substrate proteins. Several Cul4 E3 ligase complexes have been identified as important in cell cycle regulation and the DNA damage checkpoint response.

Gene ID: 8451

NCBI Accession: NP_001008895

UniProt: Q13619