BCAS3 antibody (C-Term)

Catalog No. ABIN7453844

The Rabbit Polyclonal anti-BCAS3 antibody has been validated for WB, IP and IHC (fp). It is suitable to detect BCAS3 in samples from Human.

Quick Overview for BCAS3 antibody (C-Term) (ABIN7453844)

Target: BCAS3 (Breast Carcinoma Amplified Sequence 3 (BCAS3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCAS3 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-BCAS3 Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-BCAS3 Antibody, Affinity Purified

Predicted Reactivity: Mouse

Purification: Affinity Purified

Immunogen: between AA 870 and C-term

Isotype: IgG

Application Details

Application Notes:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 or Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for BCAS3

Target: BCAS3 (Breast Carcinoma Amplified Sequence 3 (BCAS3))

Alternative Name: BCAS3

Background: Background: Breast cancer amplified sequence 3 (BCAS3) was identified as a gene overexpressed and amplified in breast cancer cell lines. BCAS3 expression has been shown to be regulated by estrogen receptor alpha (ER alpha) and its coregulator PELP1 (proline-, glutamic acid-, and leucine-rich protein 1). BCAS3 has also been demonstrated to act as a coactivator of ER alpha activity in breast cancer cells and associate with the histone acetyltransferase complex protein P/CAF (p300/CBP-associated factor).

Gene ID: 54828

UniProt: Q9H6U6