HDAC3 antibody (C-Term)

Catalog No. ABIN7453872

This anti-HDAC3 antibody is a Rabbit Polyclonal antibody detecting HDAC3 in WB, IP and IHC (fp). Suitable for Human and Mouse.

Quick Overview for HDAC3 antibody (C-Term) (ABIN7453872)

Target: HDAC3 (Histone Deacetylase 3 (HDAC3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HDAC3 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-HDAC3 Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-HDAC3 Antibody, Affinity Purified

Predicted Reactivity: Rat,Orangutan

Purification: Affinity Purified

Immunogen: between AA 375 and C-term

Isotype: IgG

Application Details

Application Notes:

IHC: 1:100 - 1:500. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:5,000 - 1:15,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for HDAC3

Target: HDAC3 (Histone Deacetylase 3 (HDAC3))

Alternative Name: HDAC3

Background: Background: Histone deacetylase 3 (HDAC3) is a class I histone deacetylase that catalyzes the removal of the acetyl group on lysine residues of the N-terminus of the core histones H2A, H2B, H3, and H4. HDAC3 is found in multi-protein complexes and its activity depends on its interaction with the co-repressors SMRT and N-CoR.

Gene ID: 8841

NCBI Accession: NP_003874

UniProt: O15379

Pathways: Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development