Recombinant FGL1 antibody (AA 18-312)

Catalog No. ABIN7453972

The Rabbit Monoclonal anti-FGL1 antibody has been validated for WB, IHC, IP and ICC. It is suitable to detect FGL1 in samples from Human.

Quick Overview for Recombinant FGL1 antibody (AA 18-312) (ABIN7453972)

Target: FGL1 (Fibrinogen-Like 1 (FGL1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This FGL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: BLR210K

Product Details anti-FGL1 Antibody

Binding Specificity: AA 18-312

Purpose: Rabbit anti-Hepassocin/FGL1 Recombinant Monoclonal Antibody [BLR210K]

Immunogen: residues 18-312 (full length)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for FGL1

Target: FGL1 (Fibrinogen-Like 1 (FGL1))

Alternative Name: Hepassocin/FGL1

Background: Background: Hepassocin, also known as Fibrinogen-like 1 (FGL1), is a member of the fibrinogen family whose members share a fibrinogen domain at their C-termini. However, it lacks the platelet-binding site, cross-linking region and thrombin-sensitive site which are necessary for fibrin clot formation. Hepassocin/FGL1 is secreted by hepatocytes and may play a role in the development of hepatocellular carcinomas. Hepassocin/FGL1 is an immune suppressive molecule that inhibits antigen-specific T-cell activation by acting as a major ligand of LAG3 [taken from NCBI Entrez Gene (Gene ID: 2267)].

Gene ID: 2267

NCBI Accession: NP_004458

UniProt: Q08830