Recombinant Cadherin 5 antibody (AA 25-595)

Catalog No. ABIN7453992

This Rabbit Monoclonal antibody specifically detects Cadherin 5 in WB, IHC, IP and ICC. It exhibits reactivity toward Mouse.

Quick Overview for Recombinant Cadherin 5 antibody (AA 25-595) (ABIN7453992)

Target: Cadherin 5 (CDH5)

Antibody Type: Recombinant Antibody

Reactivity: Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Cadherin 5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: BLR239K

Product Details anti-Cadherin 5 Antibody

Binding Specificity: AA 25-595

Purpose: Rabbit anti-VE-Cadherin Recombinant Monoclonal Antibody [BLR239K]

Immunogen: residues 25-595 (ECD)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Cadherin 5

Target: Cadherin 5 (CDH5)

Alternative Name: VE-Cadherin

Background: Background: Cadherins are calcium-dependent cell adhesion proteins that preferentially interact with themselves in a homophilic manner in adjacent cells. VE-Cadherin, or Cadherin-5 plays an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton and acts in concert with KRIT1 and MPP5 to establish and maintain correct endothelial cell polarity and vascular lumen. [taken from the Universal Protein Resource (UniProt) P33151].

Gene ID: 12562

NCBI Accession: NP_033998

UniProt: P55284

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2