ZAK antibody (AA 750-800)

Catalog No. ABIN7454426

This anti-ZAK antibody is a Rabbit Polyclonal antibody detecting ZAK in IP and IHC (fp). Suitable for Human.

Quick Overview for ZAK antibody (AA 750-800) (ABIN7454426)

Target: ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZAK antibody is un-conjugated

Application: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-ZAK Antibody

Binding Specificity: AA 750-800

Purpose: Rabbit anti-ZAK Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 750 and 800

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-ZAK antibody A301-993A.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for ZAK

Target: ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))

Alternative Name: ZAK

Background: Background: Leucine-zipper and sterile-alpha motif kinase (ZAK) is a mitogen activated protein kinase kinase kinase involved in the S and G2 phase cell cycle checkpoint. ZAK has been shown to activate the stress-activated protein kinase (c-jun N-terminal kinase) pathway and NF-kappaB. It has also been found to be a key mediator of cardiomyocyte hypertrophy and myocardial scars.

Gene ID: 51776

NCBI Accession: NP_057737

UniProt: Q9NYL2