FOXC1 antibody (AA 275-325)

Catalog No. ABIN7454490

This Rabbit Polyclonal antibody specifically detects FOXC1 in IP and IHC (fp). It exhibits reactivity toward Human.

Quick Overview for FOXC1 antibody (AA 275-325) (ABIN7454490)

Target: FOXC1 (Forkhead Box C1 (FOXC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXC1 antibody is un-conjugated

Application: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-FOXC1 Antibody

Binding Specificity: AA 275-325

Purpose: Rabbit anti-FOXC1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 275 and 325

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: Not recommended

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for FOXC1

Target: FOXC1 (Forkhead Box C1 (FOXC1))

Alternative Name: FOXC1

Background: Background: Forkhead box C1 (FOXC1) belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of FOXC1 has not yet been determined, however, the gene has been shown to play a role in the regulation of embryonic and ocular development. Mutations in the FOXC1 gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly.[taken from NCBI Entrez Gene (Gene ID: 2296)].

Gene ID: 2296

NCBI Accession: NP_001444

UniProt: Q12948

Pathways: Chromatin Binding, Glycosaminoglycan Metabolic Process