KIAA0101 antibody (AA 1-50)

Catalog No. ABIN7454508

This Rabbit Polyclonal antibody specifically detects KIAA0101 in IP and IHC (fp). It exhibits reactivity toward Human.

Quick Overview for KIAA0101 antibody (AA 1-50) (ABIN7454508)

Target: KIAA0101 (PAF) (PCNA Clamp Associated Factor (PAF))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIAA0101 antibody is un-conjugated

Application: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-KIAA0101 Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit anti-PAF Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: Not recommended. Use rabbit anti-PAF antibody A304-374A.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for KIAA0101

Target: KIAA0101 (PAF) (PCNA Clamp Associated Factor (PAF))

Alternative Name: PAF

Background: Background: PCNA associated factor (PAF) is a PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork-blocking lesions  [taken from the Universal Protein Resource (UniProt) Q15004].

Gene ID: 9768

NCBI Accession: NP_055551

UniProt: Q15004

Pathways: Chromatin Binding