HDAC7 antibody (AA 425-475)

Catalog No. ABIN7454533

The Rabbit Polyclonal anti-HDAC7 antibody has been validated for WB and IHC (fp). It is suitable to detect HDAC7 in samples from Human.

Quick Overview for HDAC7 antibody (AA 425-475) (ABIN7454533)

Target: HDAC7 (Histone Deacetylase 7 (HDAC7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HDAC7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-HDAC7 Antibody

Binding Specificity: AA 425-475

Purpose: Rabbit anti-HDAC7 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 425 and 475

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for HDAC7

Target: HDAC7 (Histone Deacetylase 7 (HDAC7))

Alternative Name: HDAC7

Background: Background: Histone deacetylase 7 (HDAC7) is a class II histone deacetylase that catalyzes the removal of acetyl groups from core histone octamer subunits. HDAC7 appears to have an influence on cellular processes by acting as a transcriptional repressor. HDAC7 is highly expressed in double positive thymocytes and may play an important role in T-cell development. Recently, HDAC7 has also been reported to influence endothelial cell migration and modulate angiogenesis.

Gene ID: 51564

NCBI Accession: NP_056216

UniProt: Q8WUI4

Pathways: Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development