CCAR1 antibody (AA 1-50)

Catalog No. ABIN7454629

The Rabbit Polyclonal anti-CCAR1 antibody has been validated for WB, IP and IHC (fp). It is suitable to detect CCAR1 in samples from Human and Mouse.

Quick Overview for CCAR1 antibody (AA 1-50) (ABIN7454629)

Target: CCAR1 (Cell Division Cycle and Apoptosis Regulator 1 (CCAR1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCAR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-CCAR1 Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit anti-CCAR1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 1 - 10 μg/mg lysate

WB: 1:5,000 - 1:15,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CCAR1

Target: CCAR1 (Cell Division Cycle and Apoptosis Regulator 1 (CCAR1))

Alternative Name: CCAR1

Background: Background: CCAR1 was identified as a perinuclear phosphoprotein that regulates apoptosis signals in response to chemotherapeutic agents. Induction of apoptosis by CCAR1 involves the epidermal growth factor receptor (EGFR), mitogen-activated protein kinase pathway and caspase-9 activation. CARP-1 has also been demonstrated as a suppressor of human breast cancer growth.

Gene ID: 55749

UniProt: Q8IX12, Q6X935