FOXP1 antibody (AA 627-677)

Catalog No. ABIN7454845

The Rabbit Polyclonal anti-FOXP1 antibody has been validated for WB, IP and IHC (fp). It is suitable to detect FOXP1 in samples from Human and Mouse.

Quick Overview for FOXP1 antibody (AA 627-677) (ABIN7454845)

Target: FOXP1 (Forkhead Box P1 (FOXP1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-FOXP1 Antibody

Binding Specificity: AA 627-677

Purpose: Rabbit anti-FOXP1 Antibody, Affinity Purified

Predicted Reactivity: Rat,Bovine

Purification: Affinity Purified

Immunogen: between AA 627 and 677

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for FOXP1

Target: FOXP1 (Forkhead Box P1 (FOXP1))

Alternative Name: FOXP1

Background: Background: FOXP1 (forkhead box protein P1) is a member of the forkhead box (FOX) subfamily P family of proteins. FoxP1 functions as a transcriptional repressor and plays an important role in the specification and differentiation of lung epithelium. It can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Additionally, FOXP1 is an essential transcriptional regulator of B cell development [taken from the Universal Protein Resource (UniProt) Q9H334].

Gene ID: 27086

NCBI Accession: NP_116071

UniProt: Q9H334

Pathways: Chromatin Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response