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Recombinant CD247 antibody (C-Term)

This Rabbit Monoclonal antibody specifically detects CD247 in WB, IP, IF (p) and IHC (fp). It exhibits reactivity toward Human.
Catalog No. ABIN7455240

Quick Overview for Recombinant CD247 antibody (C-Term) (ABIN7455240)

Target

See all CD247 Antibodies
CD247 (CD247 Molecule (CD247))

Antibody Type

Recombinant Antibody

Reactivity

  • 83
  • 39
  • 16
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Host

  • 66
  • 14
  • 5
  • 1
Rabbit

Clonality

  • 63
  • 23
Monoclonal

Conjugate

  • 54
  • 6
  • 6
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This CD247 antibody is un-conjugated

Application

  • 60
  • 44
  • 28
  • 16
  • 11
  • 9
  • 7
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone

BL-336-1B2
  • Binding Specificity

    • 13
    • 8
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Purpose

    Rabbit anti-CD247/CD3Z Recombinant Monoclonal Antibody [BL-336-1B2]

    Predicted Reactivity

    Mouse,Sheep,Pig

    Immunogen

    between AA 150 to 164 (C-term)

    Isotype

    IgG
  • Application Notes

    IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 20 μL/mg lysate

    WB: 17:40:00

    Restrictions

    For Research Use only
  • Concentration

    100 μg/mL

    Buffer

    Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C

    Expiry Date

    12 months
  • Target

    CD247 (CD247 Molecule (CD247))

    Alternative Name

    CD247/CD3Z

    Background

    Background: T-cell surface glycoprotein CD3 zeta chain is encoded by the gene CD247, also known as CD3Z or CD3 zeta. CD247/CD3 zeta, together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response [taken from NCBI Entrez Gene (Gene ID: 919)].

    Gene ID

    919

    NCBI Accession

    NP_932170

    UniProt

    P20963

    Pathways

    TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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