CCR3 antibody (APC)

Catalog No. ABIN7456604

This anti-CCR3 antibody is a Mouse Monoclonal antibody detecting CCR3 in FACS. Suitable for Human.

Quick Overview for CCR3 antibody (APC) (ABIN7456604)

Target: CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CCR3 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Clone: 5E8

Product Details anti-CCR3 Antibody (APC)

Isotype: IgG2b, kappa

Application Details

Application Notes: The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Comment:

Matching Isotype Control: APC Mouse IgG2b, κ Isotype Control[MPC-11] (ABIN7469796)

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.05 % Proclin300, 1 % Protein protectant

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Target Details for CCR3

Target: CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))

Alternative Name: CD193

Background: CC CKR3, MIP1-alpha receptor like-2, eotaxin receptor,CCR,C-C chemokine receptor type 3,CD193, also known as CC-chemokine receptor 3 (CCR3), CC CKR3, MIP1-alpha receptor like-2, and eotaxin receptor, is a member of the G protein-coupled seven transmembrane receptors family. It binds to the CC chemokines eotaxin, eotaxin-2, and eotaxin-3 with high affinity. CCR3 has also been reported to bind RANTES, MCP-3, and MCP-4 with low affinity. CCR3 receptor is expressed on human eosinophils, basophils, mast cells, mononuclear phagocytes, platelets, CD34+ hematopoietic progenitor cells, Th2-like lymphocytes, and keratinocytes. CCR3 is thought to play a role in allergic diseases such as bronchial asthma and allergic rhinitis. CCR3 is a co-receptor for HIV-1 and HIV-2, and the binding of eotaxin with CCR3 has been shown to inhibit HIV infection in some cell types.

Gene ID: 1232

UniProt: P51677