Interleukin 17a antibody (PE)

Catalog No. ABIN7457181

This Mouse Monoclonal antibody specifically detects Interleukin 17a in ICFC. It exhibits reactivity toward Mouse.

Quick Overview for Interleukin 17a antibody (PE) (ABIN7457181)

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Interleukin 17a antibody is conjugated to PE

Application: Intracellular Flow Cytometry (ICFC)

Clone: 17F3

Product Details anti-Interleukin 17a Antibody (PE)

Isotype: IgG1, kappa

Application Details

Application Notes: Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

Comment:

Matching Isotype Control: PE Mouse IgG1, κ Isotype Control (ABIN7469771)

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Target Details for Interleukin 17a

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Alternative Name: IL-17A

Background: Interleukin-17A,Il17a,Ctla8,The 17F3 monoclonal antibody reacts with mouse IL-17A a 15-20 kDa cytokine expressed by Th17 cells, γδ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. IL-17A has pleiotropic effects in immunoregulation and inflammation. It plays an important role in anti-microbial and chronic inflammation by inducing cytokine and chemokine production, neutrophil influx, and the production of antibacterial peptides but it is also an inflammatory mediator in the development of autoimmune diseases including rheumatoid arthritis, asthma, multiple sclerosis, and psoriasis. The 17F3 antibody has been shown to neutralize IL-37A in vivo.

Gene ID: 16171

UniProt: Q62386