CD163 antibody (PerCP-Cy5.5)

Catalog No. ABIN7457840

This anti-CD163 antibody is a Mouse Monoclonal antibody detecting CD163 in FACS. Suitable for Human.

Quick Overview for CD163 antibody (PerCP-Cy5.5) (ABIN7457840)

Target: CD163

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD163 antibody is conjugated to PerCP-Cy5.5

Application: Flow Cytometry (FACS)

Clone: GHI-61

Product Details anti-CD163 Antibody (PerCP-Cy5.5)

Isotype: IgG1, kappa

Application Details

Application Notes: The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Comment:

Matching Isotype Control: PerCP/Cyanine5.5 Mouse IgG1, κ Isotype Control[MOPC-21] (ABIN7469766)

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.05 % Proclin300, 1 % Protein protectant

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Target Details for CD163

Target: CD163

Alternative Name: CD163

Background: GHI/61, M130, RM3/1, p155, Hemoglobin/Haptoglobin Complex Receptor, macrophage-associated antigen, ED2(rat),CD163 is a member of the group B scavenger receptor cysteine-rich superfamily, also known as GHI/61, M130, RM3/1, p155, hemoglobin-haptoglobin complex receptor, or macrophage-associated antigen. It is a 134 kD (non-reduced)/155 kD (reduced) glycoprotein primarily expressed on macrophages, Kupffer cells, monocytes, a subset of dendritic cells, and a subset of hematopoietic stem/progenitor cells. CD163 binds to haptoglobin-hemoglobin complex and TWEAK, and plays a role in clearing hemoglobin and regulating cytokine production by macrophages. Membrane CD163 can be cleaved by metalloproteinases (MMP), resulting in a soluble form. Elevated serum level of sCD163 has been implicated in many kinds of inflammatory diseases.

Gene ID: 9332

UniProt: Q86VB7