CD3 antibody

Catalog No. ABIN7457854

The Rat Monoclonal anti-CD3 antibody has been validated for FACS. It is suitable to detect CD3 in samples from Mouse.

Quick Overview for CD3 antibody (ABIN7457854)

Target: CD3

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD3 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: 17A2

Product Details anti-CD3 Antibody

Purification: Purified

Sterility: 0.2 μm filtered

Endotoxin Level: Low Endotoxin: Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Matching Isotype Control: AF/LE Purified Rat IgG2b, κ Isotype Control (ABIN7469855)

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE)

Preservative: Azide free

Storage: 4 °C

Storage Comment: Store at 2~8°C. Do not freeze.

Target Details for CD3

Target: CD3

Alternative Name: CD3

Background: T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain,CD3E/D/G/Z,CD3e/d/g/z,CD3E/D/G/Z,CD3,CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

Gene ID: 12502

UniProt: P04235, P11942, P22646, P24161

Pathways: TCR Signaling, Ubiquitin Proteasome Pathway