CD28 antibody

Catalog No. ABIN7457870

The Golden Syrian Hamster Monoclonal anti-CD28 antibody (Clone 37-51) (ABIN7457870) specifically detects CD28 in FACS, Act and BR. The antibody is reactive with Mouse samples.

Quick Overview for CD28 antibody (ABIN7457870)

Target: CD28

Reactivity: Mouse

Host: Golden Syrian Hamster

Clonality: Monoclonal

Conjugate: This CD28 antibody is un-conjugated

Application: Flow Cytometry (FACS), Activation (Act), Blocking Reagent (BR)

Clone: 37-51

Product Details anti-CD28 Antibody

Purification: Purified

Sterility: 0.2 μm filtered

Endotoxin Level: Low Endotoxin: Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Matching Isotype Control: AF/LE Purified Syrian Hamster IgG Control (ABIN7469728)

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE)

Preservative: Azide free

Storage: 4 °C

Storage Comment: Store at 2~8°C. Do not freeze.

Target Details for CD28

Target: CD28

Alternative Name: CD28

Background: T-cell-specific surface glycoprotein CD28,Cd28,CD28,CD28 is a 44 kD glycoprotein, also known as Tp44 or T44. It is a member of the Ig superfamily, expressed on thymocytes, most peripheral T cells, and NK cells. In association with CD80 (B7-1) and CD86 (B7-2), CD28 acts as the second signal for T and NK cell activation and proliferation. The 37.51 antibody has been reported to augment in vitro T cell proliferation and cytokine production, and promote CTL development.

Gene ID: 12487

UniProt: P31041

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response