DCK antibody

Catalog No. ABIN7464354

This Mouse Monoclonal antibody specifically detects DCK in WB, IF, IP, IHC (p) and ICC. It exhibits reactivity toward Human.

Quick Overview for DCK antibody (ABIN7464354)

Target: DCK (Deoxycytidine Kinase (DCK))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DCK antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Clone: GT10412

Product Details anti-DCK Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Affinity purified by Protein A.

Immunogen: Recombinant protein encompassing a sequence within the center region of human DCK. The exact sequence is proprietary.

Isotype: IgG2b

Application Details

Application Notes: WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A549 , H1299 , HCT116 , Neuro 2A , C8D30 , NIH-3T3 , Raw264.7 , PC-12 , Rat2 , 293T , A431 , HeLa , HepG2 , DCK-transfected 293T

Validation: Overexpression

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2.01 mg/mL

Buffer: PBS, No Preservative

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for DCK

Target: DCK (Deoxycytidine Kinase (DCK))

Alternative Name: deoxycytidine kinase

Background: Deoxycytidine kinase,Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. [provided by RefSeq]

Molecular Weight: 31 kDa

Gene ID: 1633

UniProt: P27707