TUBA3C antibody

Catalog No. ABIN7465230

This Rabbit Polyclonal antibody specifically detects TUBA3C in WB. It exhibits reactivity toward Human.

Quick Overview for TUBA3C antibody (ABIN7465230)

Target: TUBA3C (Tubulin, Alpha, 3C (TUBA3C))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TUBA3C antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TUBA3C Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human TUBA3C. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , A431 , HeLa , HepG2 , NT2D1

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for TUBA3C

Target: TUBA3C (Tubulin, Alpha, 3C (TUBA3C))

Alternative Name: tubulin alpha 3c

Background: Tubulin alpha 3c , TUBA2 , bA408E5.3,Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene is an alpha tubulin gene that encodes a protein 99 % identical to the mouse testis-specific Tuba3 and Tuba7 gene products. This gene is located in the 13q11 region, which is associated with the genetic diseases Clouston hidrotic ectodermal dysplasia and Kabuki syndrome. [provided by RefSeq]

Molecular Weight: 50 kDa

Gene ID: 7278

UniProt: P0DPH7, P0DPH8

Pathways: Microtubule Dynamics