CDCA4 antibody

Catalog No. ABIN7466134

The Rabbit Polyclonal anti-CDCA4 antibody has been validated for WB. It is suitable to detect CDCA4 in samples from Human.

Quick Overview for CDCA4 antibody (ABIN7466134)

Target: CDCA4 (Cell Division Cycle Associated 4 (CDCA4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDCA4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CDCA4 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human CDCA4. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for CDCA4

Target: CDCA4 (Cell Division Cycle Associated 4 (CDCA4))

Alternative Name: cell division cycle associated 4

Background: Cell division cycle associated 4 , HEPP , SEI-3/HEPP,This gene encodes a protein that belongs to the E2F family of transcription factors. This protein regulates E2F-dependent transcriptional activation and cell proliferation, mainly through the E2F/retinoblastoma protein pathway. It also functions in the regulaton of JUN oncogene expression. This protein shows distinctive nuclear-mitotic apparatus distribution, it is involved in spindle organization from prometaphase, and may also play a role as a midzone factor involved in chromosome segregation or cytokinesis. Two alternatively spliced transcript variants encoding the same protein have been noted for this gene. Two pseudogenes have also been identified on chromosome 1. [provided by RefSeq]

Molecular Weight: 26 kDa

Gene ID: 55038

UniProt: Q9BXL8