PUS1 antibody

Catalog No. ABIN7466757

This Rabbit Polyclonal antibody specifically detects PUS1 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for PUS1 antibody (ABIN7466757)

Target: PUS1 (Pseudouridylate Synthase 1 (PUS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PUS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PUS1 Antibody

Cross-Reactivity: Human, Mouse

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PUS1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Mouse brain , A431

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PUS1

Target: PUS1 (Pseudouridylate Synthase 1 (PUS1))

Alternative Name: pseudouridine synthase 1

Background: Pseudouridine synthase 1 , MLASA1,PUS1 converts uridine into pseudouridine after the nucleotide has been incorporated into RNA. Pseudouridine may have a functional role in tRNAs and may assist in the peptidyl transfer reaction of rRNAs (Chen and Patton, 1999 [PubMed 10094309]).[supplied by OMIM]

Molecular Weight: 47 kDa

Gene ID: 80324

UniProt: Q9Y606