RORB antibody (N-Term)

Catalog No. ABIN7466783

This anti-RORB antibody is a Rabbit Polyclonal antibody detecting RORB in WB and IHC (fro). Suitable for Human.

Quick Overview for RORB antibody (N-Term) (ABIN7466783)

Target: RORB (RAR-Related Orphan Receptor B (RORB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RORB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-RORB Antibody

Binding Specificity: N-Term

Cross-Reactivity: Human, Mouse

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human ROR beta. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-Fr: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Mouse brain , HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for RORB

Target: RORB (RAR-Related Orphan Receptor B (RORB))

Alternative Name: RAR related orphan receptor B

Background: RAR related orphan receptor B , NR1F2 , ROR-BETA , RZR-BETA , RZRB , bA133M9.1,The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation. [provided by RefSeq]

Molecular Weight: 53 kDa

Gene ID: 6096

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway