HNRNPH2 antibody

Catalog No. ABIN7466869

The Rabbit Polyclonal anti-HNRNPH2 antibody has been validated for WB and IHC (p). It is suitable to detect HNRNPH2 in samples from Human.

Quick Overview for HNRNPH2 antibody (ABIN7466869)

Target: HNRNPH2 (Heterogeneous Nuclear Ribonucleoprotein H2 (H') (HNRNPH2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNRNPH2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-HNRNPH2 Antibody

Cross-Reactivity: Mouse, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human hnRNP H2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Mouse heart , Rat heart

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for HNRNPH2

Target: HNRNPH2 (Heterogeneous Nuclear Ribonucleoprotein H2 (H') (HNRNPH2))

Alternative Name: heterogeneous nuclear ribonucleoprotein H2

Background: Heterogeneous nuclear ribonucleoprotein H2 , FTP3 , HNRPH' , HNRPH2 , MRXSB , NRPH2 , hnRNPH',This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that binds to RNAs. It is very similar to the family member HNRPH1. This gene is thought to be involved in Fabray disease and X-linked agammaglobulinemia phenotype. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq]

Molecular Weight: 49 kDa

Gene ID: 3188

UniProt: P55795