MYH7 antibody (N-Term)

Catalog No. ABIN7466909

This anti-MYH7 antibody is a Rabbit Polyclonal antibody detecting MYH7 in WB. Suitable for Human.

Quick Overview for MYH7 antibody (N-Term) (ABIN7466909)

Target: MYH7 (Myosin Heavy Chain 7, Cardiac Muscle, beta (MYH7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYH7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MYH7 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Mouse, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human MYH7. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: mouse muscle

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.82 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for MYH7

Target: MYH7 (Myosin Heavy Chain 7, Cardiac Muscle, beta (MYH7))

Alternative Name: myosin heavy chain 7

Background: Myosin heavy chain 7 , CMD1S , CMH1 , MPD1 , MYHCB , SPMD , SPMM,Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy. [provided by RefSeq]

Molecular Weight: 223 kDa

Gene ID: 4625

UniProt: P12883