EPS15 antibody (C-Term)

Catalog No. ABIN7467348

This Rabbit Polyclonal antibody specifically detects EPS15 in WB. It exhibits reactivity toward Human.

Quick Overview for EPS15 antibody (C-Term) (ABIN7467348)

Target: EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPS15 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EPS15 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human, Mouse

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Eps15. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Raji , K562 , BCL-1

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.83 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for EPS15

Target: EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))

Alternative Name: epidermal growth factor receptor pathway substrate 15

Background: Epidermal growth factor receptor pathway substrate 15 , AF-1P , AF1P , MLLT5,This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq]

Molecular Weight: 99 kDa

Gene ID: 2060

UniProt: P42566

Pathways: EGFR Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, EGFR Downregulation